p53 is an important factor for the radiosensitization effect of 2-deoxy-D-glucose

• Main Authors: Chompunoot Sinthepibulyakit, Grimes, Kritopher R., Domann, Frederick E., Fang Fang, Yong Xu, Wanida Ittarat, Daret K. St. Clair, Clair, William St.
• 格式: Article
• 語言: English
• 出版: 2012
• 主題: 2-deoxy-D-glucose; p53, radiation; Lung cancer; Clonogenic survival
• 在線閱讀: https://repository.li.mahidol.ac.th/handle/123456789/2115
• 機構: Mahidol University

Metabolic change in cancer cells by preferential production of energy through glycolysis is a well-documented characteristic of cancer. However, whether inhibition of glycolysis will enhance the efficacy of radiation therapy is a matter of debate. In this study which uses lung cancer as the mod...