Relationship between plasma interleukin-12 (IL-12) and IL-18 levels and severe malarial anemia in an area of holoendemicity in western Kenya

• Main Authors: Sujittra Chaisavaneeyakorn, Caroline Othoro, Ya Ping Shi, Juliana Otieno, Sansanee C. Chaiyaroj, Altaf A. Lal, Venkatachalam Udhayakumar
• Other Authors: National Center for Infectious Diseases
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/20724
• Institution: Mahidol University

In this study, we investigated whether levels of interleukin-12 (IL-12) and IL-18 in plasma are associated with severe malarial anemia outcomes in an area of holoendemicity in western Kenya. We compared plasma IL-12 and IL-18 levels in six groups of children grouped into the categories aparasitemic,...