Vicinal dianions of diethyl α-aroylsuccinates: A general synthetic route to α-aroyl- and α-arylidene-γ-butyrolactones

Vicinal dianions derived from diethyl α-aroylsuccinates were found to react with carbonyl compounds β-regioselectively to afford α-aroyl-γ-butyrolactones, which were converted into α-arylidene-γ-butyrolactones by reduction with H2/Pd-C followed by elimination employing methanesulfonyl chloride in py...

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Main Authors:	Manat Pohmakotr, Laddawan Sampaongoen, Arisara Issaree, Patoomratana Tuchinda, Vichai Reutrakul
Other Authors:	Mahidol University
Format:	Article
Published:	2018
Subjects:	Biochemistry, Genetics and Molecular Biology Chemistry Pharmacology, Toxicology and Pharmaceutics
Online Access:	https://repository.li.mahidol.ac.th/handle/123456789/20699
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Institution:	Mahidol University

id	th-mahidol.20699
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spelling	th-mahidol.206992018-07-24T10:29:05Z Vicinal dianions of diethyl α-aroylsuccinates: A general synthetic route to α-aroyl- and α-arylidene-γ-butyrolactones Manat Pohmakotr Laddawan Sampaongoen Arisara Issaree Patoomratana Tuchinda Vichai Reutrakul Mahidol University Biochemistry, Genetics and Molecular Biology Chemistry Pharmacology, Toxicology and Pharmaceutics Vicinal dianions derived from diethyl α-aroylsuccinates were found to react with carbonyl compounds β-regioselectively to afford α-aroyl-γ-butyrolactones, which were converted into α-arylidene-γ-butyrolactones by reduction with H2/Pd-C followed by elimination employing methanesulfonyl chloride in pyridine. The method provides a general and convenient route to α-aroyl- and α-arylidene-γ-butyrolactones. © 2003 Elsevier Ltd. All rights reserved. 2018-07-24T03:19:07Z 2018-07-24T03:19:07Z 2003-08-25 Article Tetrahedron Letters. Vol.44, No.35 (2003), 6717-6720 10.1016/S0040-4039(03)01622-8 00404039 2-s2.0-0043172234 https://repository.li.mahidol.ac.th/handle/123456789/20699 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0043172234&origin=inward
institution	Mahidol University
building	Mahidol University Library
continent	Asia
country	Thailand Thailand
content_provider	Mahidol University Library
collection	Mahidol University Institutional Repository
topic	Biochemistry, Genetics and Molecular Biology Chemistry Pharmacology, Toxicology and Pharmaceutics
spellingShingle	Biochemistry, Genetics and Molecular Biology Chemistry Pharmacology, Toxicology and Pharmaceutics Manat Pohmakotr Laddawan Sampaongoen Arisara Issaree Patoomratana Tuchinda Vichai Reutrakul Vicinal dianions of diethyl α-aroylsuccinates: A general synthetic route to α-aroyl- and α-arylidene-γ-butyrolactones
description	Vicinal dianions derived from diethyl α-aroylsuccinates were found to react with carbonyl compounds β-regioselectively to afford α-aroyl-γ-butyrolactones, which were converted into α-arylidene-γ-butyrolactones by reduction with H2/Pd-C followed by elimination employing methanesulfonyl chloride in pyridine. The method provides a general and convenient route to α-aroyl- and α-arylidene-γ-butyrolactones. © 2003 Elsevier Ltd. All rights reserved.
author2	Mahidol University
author_facet	Mahidol University Manat Pohmakotr Laddawan Sampaongoen Arisara Issaree Patoomratana Tuchinda Vichai Reutrakul
format	Article
author	Manat Pohmakotr Laddawan Sampaongoen Arisara Issaree Patoomratana Tuchinda Vichai Reutrakul
author_sort	Manat Pohmakotr
title	Vicinal dianions of diethyl α-aroylsuccinates: A general synthetic route to α-aroyl- and α-arylidene-γ-butyrolactones
title_short	Vicinal dianions of diethyl α-aroylsuccinates: A general synthetic route to α-aroyl- and α-arylidene-γ-butyrolactones
title_full	Vicinal dianions of diethyl α-aroylsuccinates: A general synthetic route to α-aroyl- and α-arylidene-γ-butyrolactones
title_fullStr	Vicinal dianions of diethyl α-aroylsuccinates: A general synthetic route to α-aroyl- and α-arylidene-γ-butyrolactones
title_full_unstemmed	Vicinal dianions of diethyl α-aroylsuccinates: A general synthetic route to α-aroyl- and α-arylidene-γ-butyrolactones
title_sort	vicinal dianions of diethyl α-aroylsuccinates: a general synthetic route to α-aroyl- and α-arylidene-γ-butyrolactones
publishDate	2018
url	https://repository.li.mahidol.ac.th/handle/123456789/20699
_version_	1763492947146309632

Vicinal dianions of diethyl α-aroylsuccinates: A general synthetic route to α-aroyl- and α-arylidene-γ-butyrolactones

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