Cytotoxic activities of trichothecenes isolated from an endophytic fungus belonging to order hypocreales

• Main Authors: Maneekarn Chinworrungsee, Suthep Wiyakrutta, Nongluksna Sriubolmas, Phitaya Chuailua, Apichart Suksamrarn
• 其他作者: Srinakharinwirot University
• 格式: Article
• 出版: 2018
• 主題: Biochemistry, Genetics and Molecular Biology; Chemistry; Pharmacology, Toxicology and Pharmaceutics
• 在線閱讀: https://repository.li.mahidol.ac.th/handle/123456789/18934
• 機構: Mahidol University

Bioassay-guided fractionation of the extract of the endophytic fungus KLAR 5 belonging to order Hypocreales, which was isolated from the twig of Knema laurina (Blume) Warb., resulted in the isolation of brefeldin A (1), 8-deoxy-trichothecin (2), trichothecolone (3), 7α-hydroxytrichodermol (4), and 7...