Effect of amino acid polymorphisms of house dust mite der p 2 variants on allergic sensitization

• Main Authors: Sasipa Tanyaratsrisakul, Orathai Jirapongsananuruk, Bhakkawarat Kulwanich, Hales, Belinda J., Thomas, Wayne R., Surapon Piboonpocanun
• Other Authors: Mahidol University. Institute of Molecular Biosciences
• Format: Original Article
• Language: English
• Published: 2016
• Subjects: Allergic reaction; Der p 2 Allergen; IgE binding; Open Access article
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/1837
• Institution: Mahidol University

PURPOSE: The sequence variations of the Der p 2 allergen of Dermatophagoides pteronyssinus diverge along 2 pathways with particular amino acid substitutions at positions 40,47,111, and 114. The environmental prevalence and IgE binding to Der p 2 variants differ among regions. To compare IgE binding...