α-(Phenylthio)cyclopropylation of carbonyl compounds: Preparation of α-cyclopropyl ketones

• المؤلفون الرئيسيون: Manat Pohmakotr, Jirakorn Thisayukta
• مؤلفون آخرون: Mahidol University
• التنسيق: مقال
• منشور في: 2018
• الموضوعات: Biochemistry, Genetics and Molecular Biology; Chemistry; Pharmacology, Toxicology and Pharmaceutics
• الوصول للمادة أونلاين: https://repository.li.mahidol.ac.th/handle/123456789/17880

α-Chloro-α-(phenylthio)cyclopropane and α-acetoxy-α-(phenylthio)cyclopropane were found to react with the silyl enol ethers of some ketones in the presence of Lewis acid in dichloromethane to provide α-(phenylthio)cyclopropyl ketones, which were subjected to reduction with Ra-Ni to give the correspo...