Total synthesis of diospyrol an anthelmintic drug from diospyros mollis griff

• المؤلفون الرئيسيون: C. Mahidol, B. Tarnchompoo, C. Thebtaranonth, Y. Thebtaranonth
• مؤلفون آخرون: Mahidol University
• التنسيق: مقال
• منشور في: 2018
• الموضوعات: Biochemistry, Genetics and Molecular Biology; Chemistry; Pharmacology, Toxicology and Pharmaceutics
• الوصول للمادة أونلاين: https://repository.li.mahidol.ac.th/handle/123456789/15716

Diospyrol 4 is constructed from a masked butadiene synthon, anthracene adduct 1 [R = H]. The key construction steps comprise tandem Michael addition-Dieckmann condensations, first between anion 7 and 1, and subsequently between anion 7 and 15. © 1989.