Expression of foot and mouth disease virus nonstructural polyprotein 3ABC with inactive 3C pro in Escherichia coli

• المؤلفون الرئيسيون: Ladawan Sariya, Nattarat Thangthumniyom, Worawidh Wajjwalku, Wilairat Chumsing, Pongrama Ramasoota, Porntippa Lekcharoensuk
• مؤلفون آخرون: Mahidol University
• التنسيق: مقال
• منشور في: 2018
• الموضوعات: Biochemistry, Genetics and Molecular Biology
• الوصول للمادة أونلاين: https://repository.li.mahidol.ac.th/handle/123456789/11438

Nonstructural 3ABC protein of foot and mouth disease virus (FMDV) was widely used to differentiate vaccinated from natural FMDV-infected animals. 3ABC is a polyprotein which is auto-processed to 3A, three copies of 3B and 3C pro by 3C pro protease. The 3ABC gene was cloned and expressed in Escherich...