TP53 gene mutations of lung cancer patients in upper northern Thailand and environmental risk factors

• المؤلفون الرئيسيون: Bumroongkit K., Rannala B., Traisathit P., Srikummool M., Wongchai Y., Kangwanpong D.
• التنسيق: مقال
• اللغة: English
• منشور في: 2014
• الوصول للمادة أونلاين: http://www.scopus.com/inward/record.url?eid=2-s2.0-47549116173&partnerID=40&md5=39ba5c2fbc24f674eefdafcfad4532c9; http://www.ncbi.nlm.nih.gov/pubmed/18656689; http://cmuir.cmu.ac.th/handle/6653943832/5514

TP53 mutations are observed in about 40-70% of lung cancer tissues, and the hot spot codon mutations are in exons 5 through 8. Previous studies revealed that the distinct TP53 mutational pattern between population groups may be due to different racial or exogenous factors. This research aims to iden...