Retrospective study of ALK rearrangement and clinicopathological implications in completely resected nonsmall cell lung cancer patients in northern Thailand: Role of screening with D5F3 antibodies

• المؤلفون الرئيسيون: Apichat Tantraworasin, Nirush Lertprasertsuke, Sarawut Kongkarnka, Juntima Euathrongchit, Yutthaphan Wannasopha, Somcharoen Saeteng
• التنسيق: دورية
• منشور في: 2018
• الموضوعات: Biochemistry, Genetics and Molecular Biology; Medicine
• الوصول للمادة أونلاين: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84900847210&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/53210

Background: Anaplastic lymphoma kinase (ALK) gene rearrangement in non-small cell lung cancer (NSCLC) has been intensively studied. The gold standard for ALK detection is FISH, but this is not routinely conducted in clinical practice, so that the IHC method has a role. The aim of this study was to i...