Short-lived IFN-γ effector responses, but long-lived IL-10 memory responses, to malaria in an area of low malaria endemicity

• Main Authors: Jiraprapa Wipasa, Lucy Okell, Supachai Sakkhachornphop, Chaisuree Suphavilai, Kriangkrai Chawansuntati, Witaya Liewsaree, Julius C R Hafalla, Eleanor M. Riley
• 格式: 雜誌
• 出版: 2018
• 主題: Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology
• 在線閱讀: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79952205266&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/49741

Immunity to malaria is widely believed to wane in the absence of reinfection, but direct evidence for the presence or absence of durable immunological memory to malaria is limited. Here, we analysed malaria-specific CD4+T cell responses of individuals living in an area of low malaria transmission in...