Methoxyflavone derivatives modulate the effect of TRAIL-induced apoptosis in human leukemic cell lines

• Main Authors: Wudtiwai B., Sripanidkulchai B., Kongtawelert P., Banjerdpongchai R.
• 格式: Article
• 語言: English
• 出版: 2014
• 在線閱讀: http://www.ncbi.nlm.nih.gov/pubmed/22185222; http://www.scopus.com/inward/record.url?eid=2-s2.0-83755173700&partnerID=40&md5=06843fc2613231da12ad2a0de87a74b8; http://cmuir.cmu.ac.th/handle/6653943832/3061

Background: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis in various tumor cells, but does not affect normal cells or human leukemic cells, such as MOLT-4 and U937 cells, which are relatively resistant to TRAIL. Three flavonoids extracted from the rhizome of K. pa...