Mutation in SAM domain of TP63 is associated with nonsyndromic cleft lip and palate and cleft palate

• Main Authors: Kantaputra P.N., Malaivijitnond S., Vieira A.R., Heering J., Dotsch V., Khankasikum T., Sripathomsawat W.
• 格式: Article
• 語言: English
• 出版: 2014
• 在線閱讀: http://www.scopus.com/inward/record.url?eid=2-s2.0-79956216387&partnerID=40&md5=1a3541adfb4fcfe4e353e8c69440f5e4; http://www.ncbi.nlm.nih.gov/pubmed/21567929; http://cmuir.cmu.ac.th/handle/6653943832/1046

Mutations in sterile alpha motif (SAM) domain of TP63 have been reported to be associated with ankyloblepharon-ectodermal dysplasia-cleft lip/palate syndrome and Rapp-Hodgkin syndrome. SAM domain, a protein-protein interaction module, is found in cytoplasmic signaling proteins and several transcript...