MDM2 SNP309 is associated with high grade node positive breast tumours and is in linkage disequilibrium with a novel MDM2 intron 1 polymorphism

• Main Authors: Paulin, F.E.M, O'Neill, M, McGregor, G, Cassidy, A, Ashfield, A, Ali, C.W, Munro, A.J, Baker, L, Purdie, C.A, Lane, D.P, Thompson, A.M
• 其他作者: MEDICINE
• 格式: Article
• 出版: 2020
• 主題: estrogen receptor; protein MDM2; MDM2 protein, human; tumor marker; adult; age; article; breast cancer; breast carcinogenesis; breast tumor; cancer grading; cancer susceptibility; Caucasian; clinical feature; cohort analysis; controlled study; female; gene frequency; gene linkage disequilibrium; genetic susceptibility; genotype; homozygosity; human; intron; major clinical study; male; menopause; penetrance; polymerase chain reaction; prognosis; single nucleotide polymorphism; United Kingdom; case control study; chemistry; genetic predisposition; genetics; onset age; pathology; regression analysis; Age of Onset; Breast Neoplasms; Case-Control Studies; Female; Genetic Predisposition to Disease; Genotype; Humans; Introns; Linkage Disequilibrium; Male; Menopause; Polymorphism, Single Nucleotide; Prognosis; Proto-Oncogene Proteins c-mdm2; Receptors, Estrogen; Regression Analysis; Scotland; Tumor Markers, Biological
• 在線閱讀: https://scholarbank.nus.edu.sg/handle/10635/177964
• 機構: National University of Singapore

10.1186/1471-2407-8-281