NMR binding and crystal structure reveal that intrinsically-unstructured regulatory domain auto-inhibits PAK4 by a mechanism different from that of PAK1

• Main Authors: Wang, W., Lim, L., Baskaran, Y., Manser, E., Song, J.
• 其他作者: BIOLOGICAL SCIENCES
• 格式: Article
• 出版: 2014
• 主題: Auto-inhibition; Intrinsically unstructured protein (IUP); Isothermal titration calorimetry (ITC); NMR spectroscopy; P21-activated kinases (PAKs); X-ray crystallography
• 在線閱讀: http://scholarbank.nus.edu.sg/handle/10635/101228
• 機構: National University of Singapore

10.1016/j.bbrc.2013.07.047