Study of vaults in skin biology and host defence - from in vitro to in vivo

• المؤلف الرئيسي: Lian, Yilong
• مؤلفون آخرون: Sara Sandin
• التنسيق: Theses and Dissertations
• اللغة: English
• منشور في: 2019
• الموضوعات: DRNTU::Science::Biological sciences::Molecular biology
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/95071; http://hdl.handle.net/10220/48569
• المؤسسة: Nanyang Technological University

Vault, an approximately 13 MDa ribonucleoprotein first isolated from rat liver, consists of 3 proteins, TEP1, vPARP and MVP, and a group of non-coding RNAs known as vtRNAs. Vault particles have a capsular barrel-like structure which can be formed by MVP alone. MVP, the structural protein of vaults,...