Human iPS derived progenitors bioengineered into liver organoids using an inverted colloidal crystal poly (ethylene glycol) scaffold

• Main Authors: Blackford, Samuel J. I., Ng, Soon Seng, Saeb-Parsy, Kourosh, Segal, Joe M., Serra, Maria Paola, Horcas-Lopez, Marta, No, Da Yoon, Mastoridis, Sotiris, Jassem, Wayel, Frank, Curtis W., Cho, Nam Joon, Nakauchi, Hiromitsu, Glenn, Jeffrey S., Rashid, S. Tamir
• 其他作者: School of Materials Science & Engineering
• 格式: Article
• 語言: English
• 出版: 2018
• 主題: Biomimetic Materials; Liver Stem Cells; DRNTU::Engineering::Materials::Biomaterials
• 在線閱讀: https://hdl.handle.net/10356/89834; http://hdl.handle.net/10220/46368
• 機構: Nanyang Technological University

Generation of human organoids from induced pluripotent stem cells (iPSCs) offers exciting possibilities for developmental biology, disease modelling and cell therapy. Significant advances towards those goals have been hampered by dependence on animal derived matrices (e.g. Matrigel), immortalized ce...