A new method of N to C sequential ligation using thioacid capture ligation and native chemical ligation

• Main Authors: Hou, Wen, Liu, Lei, Zhang, Xiaohong, Liu, Chuanfa
• 其他作者: School of Biological Sciences
• 格式: Article
• 語言: English
• 出版: 2019
• 主題: Science::Biological sciences; Sequential Peptide Ligation; Thioacid Capture Ligation
• 在線閱讀: https://hdl.handle.net/10356/87104; http://hdl.handle.net/10220/49869

Sequential peptide ligation strategy becomes more and more important in large protein or long peptides chemical synthesis due to the limited peptide/protein size obtained by solid phase synthesis of individual peptides or even one-step peptide ligation. Herein, we developed an alternative method whi...