A rheostat mechanism governs the bifurcation of carbon flux in mycobacteria

• المؤلفون الرئيسيون: Murima, Paul, Zimmermann, Michael, Chopra, Tarun, Pojer, Florence, Fonti, Giulia, Dal Peraro, Matteo, Alonso, Sylvie, Sauer, Uwe, Pethe, Kevin, McKinney, John D.
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2016
• الموضوعات: Bacterial genetics; Biochemical networks
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/83396; http://hdl.handle.net/10220/41416

Fatty acid metabolism is an important feature of the pathogenicity of Mycobacterium tuberculosis during infection. Consumption of fatty acids requires regulation of carbon flux bifurcation between the oxidative TCA cycle and the glyoxylate shunt. In Escherichia coli, flux bifurcation is regulated by...