Heterochromatin Protein 1 Secures Survival and Transmission of Malaria Parasites

• Main Authors: Brancucci, Nicolas M.B., Bertschi, Nicole L., Zhu, Lei, Niederwieser, Igor, Chin, Wai Hoe, Wampfler, Rahel, Freymond, Céline, Rottmann, Matthias, Felger, Ingrid, Bozdech, Zbynek, Voss, Till S.
• 其他作者: School of Biological Sciences
• 格式: Article
• 語言: English
• 出版: 2016
• 主題: Biological Sciences
• 在線閱讀: https://hdl.handle.net/10356/82524; http://hdl.handle.net/10220/40061

Clonally variant expression of surface antigens allows the malaria parasite Plasmodium falciparum to evade immune recognition during blood stage infection and secure malaria transmission. We demonstrate that heterochromatin protein 1 (HP1), an evolutionary conserved regulator of heritable gene silen...