Triflic-acid-catalyzed tandem allylic substitution–cyclization reaction of alcohols with thiophenols—facile access to polysubstituted thiochromans

• المؤلفون الرئيسيون: Abdul Sadeer, Pullarkat, Sumod Appukuttan, Shand, Sam S., Li, Yongxin, Vu, Minh Duy, Foo, Ce Qing
• مؤلفون آخرون: School of Physical and Mathematical Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2019
• الموضوعات: Science::Chemistry::Biochemistry; Thiophenols; Thiochromans
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/80539; http://hdl.handle.net/10220/50371
• المؤسسة: Nanyang Technological University

Hitherto inaccessible multisubstituted thiochroman derivatives were constructed via the one-pot reaction of thiophenols with allylic alcohols catalyzed by 0.2 equiv triflic acid under metal-free conditions. A variety of thiochroman derivatives can be obtained by this straightforward protocol that al...