The study of dopamine metabolism with LRRK2 variants in Parkinson’s disease

• المؤلف الرئيسي: Kwok, Wei Hao
• مؤلفون آخرون: Zhao Yi
• التنسيق: Final Year Project
• اللغة: English
• منشور في: 2015
• الموضوعات: DRNTU::Science::Biological sciences::Human anatomy and physiology::Neurobiology
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/65657
• المؤسسة: Nanyang Technological University

Background: Parkinson's disease (PD) is a neurodegenerative disease in which symptoms typically appear when a loss of dopaminergic (DA) neurons causes dopamine levels to fall significantly. Leucine rich repeat kinase 2 (LRRK2) gene mutations are the most common genetic cause of PD. Dopamine dec...