Molecular mechanics of asialogycoprotetin receptor interactions with ligands

• المؤلف الرئيسي: Chew, Lay Leng.
• مؤلفون آخرون: Liao, Kin
• التنسيق: Theses and Dissertations
• منشور في: 2008
• الموضوعات: DRNTU::Engineering::Bioengineering
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/5601
• المؤسسة: Nanyang Technological University

Human asialoglycoprotein receptor (ASGPR) is also known as hepatic lectin integral membrane protein, which is responsible for the clearance of desialyl galactose-terminal glycoproteins from the circulation by receptor-mediated endocytosis. Studies have shown that the main interaction of hepatocytes...