Structures, interactions and activity of the N-terminal truncated variants of antimicrobial peptide thanatin

• المؤلفون الرئيسيون: Swaleeha Jaan Abdullah, Mu, Yuguang, Bhattacharjya, Surajit
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2024
• الموضوعات: Medicine, Health and Life Sciences; Antibiotic resistance; Antimicrobial
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/174751
• المؤسسة: Nanyang Technological University

Gram-negative bacteria are intrinsically more resistant to many frontline antibiotics, which is attributed to the permeability barrier of the outer membrane, drug efflux pumps and porins. Consequently, discovery of new small molecules antibiotics to kill drug-resistant Gram-negative bacteria present...