Chemical basis of combination therapy to combat antibiotic resistance

• المؤلفون الرئيسيون: Si, Zhangyong, Pethe, Kevin, Chan-Park, Mary B.
• مؤلفون آخرون: School of Chemical and Biomedical Engineering
• التنسيق: مقال
• اللغة: English
• منشور في: 2023
• الموضوعات: Science::Chemistry::Biochemistry; Antimicrobial Resistance; Combination Therapy
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/164619

The antimicrobial resistance crisis is a global health issue requiring discovery and development of novel therapeutics. However, conventional screening of natural products or synthetic chemical libraries is uncertain. Combination therapy using approved antibiotics with inhibitors targeting innate r...