Complement factor B mediates ocular angiogenesis through regulating the VEGF signaling pathway
Complement factor B (CFB), a 95-kDa protein, is a crucial catalytic element of the alternative pathway (AP) of complement. After binding of CFB to C3b, activation of the AP depends on the proteolytic cleavage of CFB by factor D to generate the C3 convertase (C3bBb). The C3 convertase contains the ca...
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| Main Authors: | , , , |
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| 格式: | Article |
| 語言: | English |
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2022
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| 在線閱讀: | https://hdl.handle.net/10356/154019 |
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