MicroRNA-138 is a prognostic biomarker for triple-negative breast cancer and promotes tumorigenesis via TUSC2 repression

• المؤلفون الرئيسيون: Nama, Srikanth, Muhuri, Manish, Di Pascale, Federica, Quah, Shan, Aswad, Luay, Fullwood, Melissa, Sampath, Prabha
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2020
• الموضوعات: Science::Biological sciences; Breast Cancer; MicroRNA-138
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/142966

Breast cancer manifests as a spectrum of subtypes with distinct molecular signatures, and different responses to treatment. Of these subtypes, triple-negative breast cancer (TNBC) has the worst prognoses and limited therapeutic options. Here we report aberrant expression of microRNA-138 (miR-138) in...