A role for the VPS retromer in Brucella intracellular replication revealed by genomewide siRNA screening

• المؤلفون الرئيسيون: Casanova, Alain, Low, Shyan Huey, Québatte, Maxime, Sedzick, Jaroslaw, Tschon, Therese, Ketterer, Maren, Smith, Kevin, Emmenlauer, Mario, Ben-Tekaya, Houchaima, Dehio, Christoph
• مؤلفون آخرون: Lee Kong Chian School of Medicine (LKCMedicine)
• التنسيق: مقال
• اللغة: English
• منشور في: 2020
• الموضوعات: Science::Medicine; Brucella; RAB7A
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/142436

Brucella, the agent causing brucellosis, is a major zoonotic pathogen with worldwide distribution. Brucella resides and replicates inside infected host cells in membrane-bound compartments called Brucella-containing vacuoles (BCVs). Following uptake, Brucella resides in endosomal BCVs (eBCVs) that g...