Regulome of cancer epithelial-mesenchymal transition (EMT)

• المؤلف الرئيسي: See, Benedict
• مؤلفون آخرون: Tan Nguan Soon
• التنسيق: Final Year Project
• اللغة: English
• منشور في: Nanyang Technological University 2020
• الموضوعات: Science::Biological sciences::Molecular biology
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/140680
• المؤسسة: Nanyang Technological University

During metastasis, cancer cells employ autophagy to meet elevated energy demands, of which the adaptor protein 14-3-3γ may play a role in this autophagic mechanism. It is hypothesized that 14-3-3γ activity promotes autophagy and EMT, and inhibition of 14-3-3γ may lead to the prevention of metastasis...