A renal-clearable duplex optical reporter for real-time imaging of contrast-induced acute kidney injury

• المؤلفون الرئيسيون: Huang, Jiaguo, Lyu, Yan, Li, Jingchao, Cheng, Penghui, Jiang, Yuyan, Pu, Kanyi
• مؤلفون آخرون: School of Chemical and Biomedical Engineering
• التنسيق: مقال
• اللغة: English
• منشور في: 2020
• الموضوعات: Engineering::Chemical engineering; Renal-Clearable Duplex Optical Reporter; Acute Kidney Injury
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/136719
• المؤسسة: Nanyang Technological University

Despite its high morbidity and mortality, contrast‐induced acute kidney injury (CIAKI) remains a diagnostic dilemma because it relies on in vitro detection of insensitive late‐stage blood and urinary biomarkers. We report the synthesis of an activatable duplex reporter (ADR) for real‐time in vivo im...