Molecular dynamics simulations demonstrate the regulation of DNA-DNA attraction by H4 histone tail acetylations and mutations

The positively charged N-terminal histone tails play a crucial role in chromatin compaction and are important modulators of DNA transcription, recombination, and repair. The detailed mechanism of the interaction of histone tails with DNA remains elusive. To model the unspecific interaction of histon...

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Main Authors: Korolev, Nikolay, Yu, Hang, Lyubartsev, Alexander P., Nordenskiöld, Lars
其他作者: Case, David A.
格式: Article
語言:English
出版: 2015
主題:
在線閱讀:https://hdl.handle.net/10356/106867
http://hdl.handle.net/10220/25198
http://dx.doi.org/10.1002/bip.22499
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