Assessing the binding affinity of a selected class of DPP4 inhibitors using chemical descriptor-based multiple linear regression

Assessing the binding affinity of a selected class of DPP4 inhibitors using chemical descriptor-based multiple linear regression

The activity of a selected class of DPP4 inhibitors was preliminary assessed using chemical descriptors derived AM1 optimized geometries. Using multiple linear regression model, it was found that ΔE0 , LUMO energy, area, molecular weight and ΔH0 are the significant descriptors that can adequately as...

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書目詳細資料
Main Authors:	Janairo, Jose Isagani B., Janairo, Gerardo C., Co, Frumencio F., Yu, Derrick Ethelbhert C.
格式:	text
出版:	Animo Repository 2011
主題:	CD26 antigen—Inhibitors Biochemistry, Biophysics, and Structural Biology
在線閱讀:	https://animorepository.dlsu.edu.ph/faculty_research/6604
標簽:	添加標簽沒有標簽, 成為第一個標記此記錄!
機構:	De La Salle University

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