A Potent EGFR Inhibitor, N-Phenyl Pyrazoline Derivative Suppresses Aggressiveness and Cancer Stem Cell-Like Phenotype of Cervical Cancer Cells

• Main Authors: Mustofa, Mustofa, Satriyo, Pamungkas Bagus, Suma, Artania Adnin Tri, Waskitha, Stephanus Satria Wira, Wahyuningsih, Tutik Dwi, Sholikhah, Eti Nurwening
• 格式: Other NonPeerReviewed
• 語言: English
• 出版: Drug Design, Development and Therapy 2022
• 主題: Medicinal and Biomolecular Chemistry
• 在線閱讀: https://repository.ugm.ac.id/284222/1/A-Potent-EGFR-Inhibitor-NPhenyl-Pyrazoline-Derivative-Suppresses-Aggressiveness-and-Cancer-Stem-CellLike-Phenotype-of-Cervical-Cancer-CellsDrug-Design-Development-and-Therapy.pdf; https://repository.ugm.ac.id/284222/; https://pubmed.ncbi.nlm.nih.gov/35899233/

Objective: Metastasis causes approximately 90% of cancer-related deaths, including in cervical cancer patients. Uncontrolled cell proliferation, migration, and cancer stemness act as critical events in primary tumor growth and cancer metastasis progression in cervical cancer. Here, we investigated...