Understanding the Potential Impact of Different Drug Properties on Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Transmission and Disease Burden: A Modelling Analysis

• Main Authors: Whittaker, Charles, Watson, Oliver J., Alvarez-Moreno, Carlos, Angkasekwinai, Nasikarn, Boonyasiri, Adhiratha, Triana, Luis Carlos, Chanda, Duncan, Charoenpong, Lantharita, Chayakulkeeree, Methee, Cooke, Graham S., Croda, Julio, Cucunubá, Zulma M., Djaafara, Bimandra A., Estofolete, Cassia F., Grillet, Maria-Eugenia, Faria, Nuno R., Costa, Silvia Figueiredo, Forero-Peña, David A., Gibb, Diana M., Gordon, Anthony C., Hamers, Raph L., Hamlet, Arran, Irawany, Vera, Jitmuang, Anupop, Keurueangkul, Nukool, Kimani, Teresia Njoki, Lampo, Margarita, Levin, Anna S., Lopardo, Gustavo, Mustafa, Rima, Nayagam, Shevanthi, Ngamprasertchai, Thundon, Njeri, Ng'ang'a Irene Hannah, Nogueira, Mauricio L., Ortiz-Prado, Esteban, Perroud, Mauricio W., Phillips, Andrew N., Promsin, Panuwat, Qavi, Ambar, Rodger, Alison J., Sabino, Ester C., Sangkaew, Sorawat, Sari, Djayanti, Sirijatuphat, Rujipas, Sposito, Andrei C., Srisangthong, Pratthana, Thompson, Hayley A., Udwadia, Zarir, Valderrama-Beltrán, Sandra, Winskill, Peter, Ghani, Azra C., Walker, Patrick G.T., Hallett, Timothy B.
• Format: Article PeerReviewed
• Language: English
• Published: Oxford University Press 2022
• Subjects: Respiratory Diseases
• Online Access: https://repository.ugm.ac.id/283445/1/221.pdf; https://repository.ugm.ac.id/283445/; https://academic.oup.com/cid/article/75/1/e224/6373521?login=true

Background. The public health impact of the coronavirus disease 2019 (COVID-19) pandemic has motivated a rapid search for potential therapeutics, with some key successes. However, the potential impact of different treatments, and consequently research and procurement priorities, have not been clea...