SYNTHESIS OF 4-ALLYL-2-METHOXY-6-AMINOPHENOL FROM NATURAL EUGENOL Sintesis 4-AIIII-2-metoksl-6-amlnofenol darl Senyawa Bahan Alam Eugenol

• المؤلف الرئيسي: Perpustakaan UGM, i-lib
• التنسيق: مقال NonPeerReviewed
• منشور في: [Yogyakarta] : Universitas Gadjah Mada 2008
• الموضوعات: Jurnal i-lib UGM
• الوصول للمادة أونلاين: https://repository.ugm.ac.id/27974/; http://i-lib.ugm.ac.id/jurnal/download.php?dataId=11037
• المؤسسة: Universitas Gadjah Mada

ABSTRACT The aim of this preliminary research was to synthesize derivatives of eugenol such as 4-al/yl-2-methoxy-6- nitrophenol (2) and 4-al/yl-2-methoxy-6-aminophenol (3). The result could be used as a reference on the transformation of eugenol to its derivatives. Theoriticaly nitration of eugenol (1) by nitric acid could produced 4-al/yl- 2-methoxy-6-nitrophenol (2) and fol/owed by reduction could achieved 4-al/yl-2-mehtoxy-6-aminophenol (3). The formation of this product was analyzed by analytical thin layer chromatography (TLC) and GC-MS. These analysis showed the formation of product (2) and (3) were visible. TLC showed product (1) less polar than eugenol and gave orange colour, and supported by GC-MS which showed molecular ion at f!l/z 209 due to the presenceof -N02 by replacing one H at 6 position of eugenol. Product (3) was afforded by reduction of (2) with Sn/HCI and tIc analysis showed compound (3) more polar than eugenol (1) and (2) and supported by GC-MS which showed molecular ion at m/z 179 due to the presence of -NH2.