Allopurinol-Induced Stevens–Johnson Syndrome in Javanese Men With Positive HLA-B*58:01

• Main Authors: Ferdiana, Astri, Fachiroh, Jajah, Oktarina, Dyah Ayu Mira, Irwanto, Astrid, Mahendra, Caroline, Febriana, Sri Awalia, Soebono, Hardyanto
• 格式: Article PeerReviewed
• 語言: English
• 出版: Frontier 2022
• 主題: Clinical Sciences
• 在線閱讀: https://repository.ugm.ac.id/278649/1/Ferdiana_KKMK.pdf; https://repository.ugm.ac.id/278649/; https://www.frontiersin.org/articles/10.3389/fgene.2022.839154/full; https://doi.org/10.3389/fgene.2022.839154

Background: Allopurinol is the most commonly used drug for the treatment of gout arthritis. However, the use of allopurinol is associated with severe cutaneous adverse reactions (SCARs) and life-threatening immune-mediated reactions that include Stevens–Johnson syndrome (SJS). SJS induced by allopu...