PERBANDINGAN EFEK TERAPETIK CEFIXIME DALAM SEDIAAN GENERIK DAN BRANDED PADA PASIEN DENGAN INFEKSI SALURAN PERNAPASAN BAGIAN BAWAH
Bronchitis and pneumonia are lower respiratory infection that can be caused by bacteria and often occur in children. Drug product of cefixime,generic and branded,are widely used in Rajawali Citra Hospital. The use of generic for the treatment of a disease is often questionable in terms of effectiven...
Saved in:
| Main Authors: | , |
|---|---|
| 格式: | Theses and Dissertations NonPeerReviewed |
| 出版: |
[Yogyakarta] : Universitas Gadjah Mada
2014
|
| 主題: | |
| 在線閱讀: | https://repository.ugm.ac.id/133342/ http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=73956 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|
| 機構: | Universitas Gadjah Mada |
| 總結: | Bronchitis and pneumonia are lower respiratory infection that can be
caused by bacteria and often occur in children. Drug product of cefixime,generic
and branded,are widely used in Rajawali Citra Hospital. The use of generic for the
treatment of a disease is often questionable in terms of effectiveness when
compared to branded. The aim of this research is to determine the difference
between therapeutic effect of generic cefixime and branded cefixime based on the
clinical monitoring after the patients taking antibiotics.
This study was a quasi-experimental study with prospective data collection
in pediatric department Rajawali Citra RS Yogyakarta. The subjects who
fulfillinclution criteria were divided into two groups: generic cefixime group
(group A) and branded cefixime group (group B). Parameters that observed were
duration disappearance of fever, cough, cold, and other symptoms. Data were
analyzed using unpaired student�s t-test with a level of 95%.
The average of fever disappearance duration in each group are not
statistically different (p >0.05). The average of fever disappearance duration in
group A is 3.30 days and 3.16 days in group B. The disappearance duration of
cough in each group are not statistically different (p>0.05). The average of cough
disappearanceduration in group A is 5.92 days and 5.84 days in group B. The
disappearance duration of cold in each group are not statistically different (p
>0,05). The average of cold disappearance duration in group A is 5.89 days and
5.95 days in group B. The disappearanceduration of other symptoms in each
group are not statistically different (p > 0,05). The average of other symptom
disappearanceduration in group A is 3.0 days and 3.05 days in group B.
There were no differences therapeutic effects between generic cefixime
and branded cefixime based on the observed patient's clinical symptoms.
Disappearance of fever, cough, cold, and other symptoms in both groups had the
duration (days) were almost the same. |
|---|