PEMODELAN STOKASTIK REGULASI GEN DALAM MERESPON GRADED HYPOXIA DENGAN CONTINUOUS-TIME MARKOV CHAIN

• Main Authors: , Putu Indah Ciptayani, , Dr.-Ing. MHD. Reza M.I. Pulungan, S.Si., M.Sc
• Format: Theses and Dissertations NonPeerReviewed
• Published: [Yogyakarta] : Universitas Gadjah Mada 2012
• Subjects: ETD
• Online Access: https://repository.ugm.ac.id/101021/; http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=57506
• Institution: Universitas Gadjah Mada

Hypoxia is a pathological condition in which a whole or a region of the body is deprived of adequate oxygen supply. Hypoxia inducible factor (HIF) is a main protein involved in adaptation to low oxygen pressure. There are two oxygen sensors, prolyl hydroxylase (PHD) and factor inhibitting HIF (FIH)....