Penelusuran Mekanisme Molekuler Peningkatan Sensitivitas Sel MCF-7/DOX Terhadap Doxorubicin Oleh Naringenin Melalui Regulasi Ekspresi P-Glikoprotein Dan Interaksinya Pada Protein Kinase

• Main Authors: , DYANINGTYAS DEWI PAMUNGKAS PUTRI, , Dr. Ratna Asmah Susidarti, M.Si., Apt.
• Format: Theses and Dissertations NonPeerReviewed
• Published: [Yogyakarta] : Universitas Gadjah Mada 2012
• Subjects: ETD
• Online Access: https://repository.ugm.ac.id/100907/; http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=57837

Naringenin, an abundant flavanon in the peel of citrus fruits is reported to possess anti-proliferative effect in many cancer cells. Herein, we investigated the cytotoxic effect and apoptosis induction of naringenin in combination with doxorubicin on MCF-7/DOX cells to increase sensitivity of doxoru...