PENGARUH KADAR ASAM OLEAT, ISOPROPIL ALKOHOL, DAN PROPILEN GLIKOL TERHADAP KARAKTERISTIK FISIKOKIMIA PATCH KALIUM LOSARTAN DENGAN POLIMER MATRIKS HYDROXYPROPYL METHYLCELLULOSE DAN POLYVYNIL ALCOHOL BESERTA PROFIL TRANSPOR TRANSDERMAL IN VITRO

• المؤلفون الرئيسيون: , RINA WIDIASTUTI, , Dr. Akhmad Kharis Nugroho, M.Si., Apt
• التنسيق: Theses and Dissertations NonPeerReviewed
• منشور في: [Yogyakarta] : Universitas Gadjah Mada 2012
• الموضوعات: ETD
• الوصول للمادة أونلاين: https://repository.ugm.ac.id/100900/; http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=57728

Losartan, one of the potent angiotensin II receptor antagonist has a low bioavailability (33%) due to intensive metabolism in the liver. Therefore, the transdermal delivery system could be one alternative efforts to improve the bioavailability of the drug. The aimed of this study was to determine th...