Antimalarial and Antioxidant Activities of Isoprenylated Coumarins from the Stem Bark of Mesua borneensis L.

The aim of this study was to assess the antimalarial and antioxidant effects of the n-hexane and ethyl acetate extracts together with three isolated isoprenylated coumarins, mammea A/BA(1),mammea A/ AA cyclo D (2) and mesuol (3) from the stem bark of M. borneensis L. The n-hexane and ethyl acetate e...

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Main Authors: Mulyadi Tanjung, Ratih Dewi Saputri, Faiz Fakhriah Fitriati, Tjitjik Srie Tjahjandarie
格式: Article PeerReviewed
語言:English
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出版: Taylor & Francis Online 2016
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在線閱讀:http://repository.unair.ac.id/90946/1/C.10.%20Abstract.pdf
http://repository.unair.ac.id/90946/2/C.10.%20Fulltext%20%28Karya%20Ilmiah%29.pdf
http://repository.unair.ac.id/90946/3/C10_Validasi__Antimalarial%20and%20Antioxidant%20Activities.pdf
http://repository.unair.ac.id/90946/4/C10_Similarity.pdf
http://repository.unair.ac.id/90946/
https://www.tandfonline.com/doi/abs/10.1080/22311866.2016.1188726
http://dx.doi.org/10.1080/22311866.2016.1188726
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spelling id-langga.909462020-03-09T01:53:35Z http://repository.unair.ac.id/90946/ Antimalarial and Antioxidant Activities of Isoprenylated Coumarins from the Stem Bark of Mesua borneensis L. Mulyadi Tanjung Ratih Dewi Saputri Faiz Fakhriah Fitriati Tjitjik Srie Tjahjandarie Q Science (General) QD Chemistry The aim of this study was to assess the antimalarial and antioxidant effects of the n-hexane and ethyl acetate extracts together with three isolated isoprenylated coumarins, mammea A/BA(1),mammea A/ AA cyclo D (2) and mesuol (3) from the stem bark of M. borneensis L. The n-hexane and ethyl acetate extracts, as well as compounds 1-3 were evaluated for their antimalarial activity against Plasmodium falciparum strain 3D7 (chloroquine-sensitive) and their antioxidant activity against DPPH radical scavenging. Compound 2 exhibited slightly more active than chloroquine. Compounds 1 and 3 showed very high activity against DPPH radical. Taylor & Francis Online 2016-03 Article PeerReviewed image en http://repository.unair.ac.id/90946/1/C.10.%20Abstract.pdf text en http://repository.unair.ac.id/90946/2/C.10.%20Fulltext%20%28Karya%20Ilmiah%29.pdf text en http://repository.unair.ac.id/90946/3/C10_Validasi__Antimalarial%20and%20Antioxidant%20Activities.pdf text en http://repository.unair.ac.id/90946/4/C10_Similarity.pdf Mulyadi Tanjung and Ratih Dewi Saputri and Faiz Fakhriah Fitriati and Tjitjik Srie Tjahjandarie (2016) Antimalarial and Antioxidant Activities of Isoprenylated Coumarins from the Stem Bark of Mesua borneensis L. Journal of Biologically Active Products from Nature, 6 (2). pp. 95-100. ISSN 2231-1866 https://www.tandfonline.com/doi/abs/10.1080/22311866.2016.1188726 http://dx.doi.org/10.1080/22311866.2016.1188726
institution Universitas Airlangga
building Universitas Airlangga Library
country Indonesia
collection UNAIR Repository
language English
English
English
English
topic Q Science (General)
QD Chemistry
spellingShingle Q Science (General)
QD Chemistry
Mulyadi Tanjung
Ratih Dewi Saputri
Faiz Fakhriah Fitriati
Tjitjik Srie Tjahjandarie
Antimalarial and Antioxidant Activities of Isoprenylated Coumarins from the Stem Bark of Mesua borneensis L.
description The aim of this study was to assess the antimalarial and antioxidant effects of the n-hexane and ethyl acetate extracts together with three isolated isoprenylated coumarins, mammea A/BA(1),mammea A/ AA cyclo D (2) and mesuol (3) from the stem bark of M. borneensis L. The n-hexane and ethyl acetate extracts, as well as compounds 1-3 were evaluated for their antimalarial activity against Plasmodium falciparum strain 3D7 (chloroquine-sensitive) and their antioxidant activity against DPPH radical scavenging. Compound 2 exhibited slightly more active than chloroquine. Compounds 1 and 3 showed very high activity against DPPH radical.
format Article
PeerReviewed
author Mulyadi Tanjung
Ratih Dewi Saputri
Faiz Fakhriah Fitriati
Tjitjik Srie Tjahjandarie
author_facet Mulyadi Tanjung
Ratih Dewi Saputri
Faiz Fakhriah Fitriati
Tjitjik Srie Tjahjandarie
author_sort Mulyadi Tanjung
title Antimalarial and Antioxidant Activities of Isoprenylated Coumarins from the Stem Bark of Mesua borneensis L.
title_short Antimalarial and Antioxidant Activities of Isoprenylated Coumarins from the Stem Bark of Mesua borneensis L.
title_full Antimalarial and Antioxidant Activities of Isoprenylated Coumarins from the Stem Bark of Mesua borneensis L.
title_fullStr Antimalarial and Antioxidant Activities of Isoprenylated Coumarins from the Stem Bark of Mesua borneensis L.
title_full_unstemmed Antimalarial and Antioxidant Activities of Isoprenylated Coumarins from the Stem Bark of Mesua borneensis L.
title_sort antimalarial and antioxidant activities of isoprenylated coumarins from the stem bark of mesua borneensis l.
publisher Taylor & Francis Online
publishDate 2016
url http://repository.unair.ac.id/90946/1/C.10.%20Abstract.pdf
http://repository.unair.ac.id/90946/2/C.10.%20Fulltext%20%28Karya%20Ilmiah%29.pdf
http://repository.unair.ac.id/90946/3/C10_Validasi__Antimalarial%20and%20Antioxidant%20Activities.pdf
http://repository.unair.ac.id/90946/4/C10_Similarity.pdf
http://repository.unair.ac.id/90946/
https://www.tandfonline.com/doi/abs/10.1080/22311866.2016.1188726
http://dx.doi.org/10.1080/22311866.2016.1188726
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