Antimalarial and Antioxidant Activities of Isoprenylated Coumarins from the Stem Bark of Mesua borneensis L.

The aim of this study was to assess the antimalarial and antioxidant effects of the n-hexane and ethyl acetate extracts together with three isolated isoprenylated coumarins, mammea A/BA(1),mammea A/ AA cyclo D (2) and mesuol (3) from the stem bark of M. borneensis L. The n-hexane and ethyl acetate e...

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Main Authors:	Tanjung, Mulyadi, Saputri, Ratih Dewi, Fitriati, Faiz Fakhriah, Tjahjandarie, Tjitjik Srie
Format:	Article PeerReviewed
Language:	English English English
Published:	Har Krishan Bhalla & Sons 2016
Subjects:	QD Chemistry
Online Access:	http://repository.unair.ac.id/63045/1/Cover.pdf http://repository.unair.ac.id/63045/2/Bukti%20C15.%20Antimalarial%20and%20Antioxidant%20Activities%20of%20Isoprenylated%20..........pdf http://repository.unair.ac.id/63045/3/Bukti%20C15%20Peer%20reviewer%20dan%20validasi%20Kadep.pdf http://repository.unair.ac.id/63045/ http://dx.doi.org/10.1080/22311866.2016.1188726
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spelling	id-langga.630452017-10-12T23:42:29Z http://repository.unair.ac.id/63045/ Antimalarial and Antioxidant Activities of Isoprenylated Coumarins from the Stem Bark of Mesua borneensis L. Tanjung, Mulyadi Saputri, Ratih Dewi Fitriati, Faiz Fakhriah Tjahjandarie, Tjitjik Srie QD Chemistry The aim of this study was to assess the antimalarial and antioxidant effects of the n-hexane and ethyl acetate extracts together with three isolated isoprenylated coumarins, mammea A/BA(1),mammea A/ AA cyclo D (2) and mesuol (3) from the stem bark of M. borneensis L. The n-hexane and ethyl acetate extracts, as well as compounds 1-3 were evaluated for their antimalarial activity against Plasmodium falciparum strain 3D7 (chloroquine-sensitive) and their antioxidant activity against DPPH radical scavenging. Compound 2 exhibited slightly more active than chloroquine. Compounds 1 and 3 showed very high activity against DPPH radical. Har Krishan Bhalla & Sons 2016 Article PeerReviewed image en http://repository.unair.ac.id/63045/1/Cover.pdf text en http://repository.unair.ac.id/63045/2/Bukti%20C15.%20Antimalarial%20and%20Antioxidant%20Activities%20of%20Isoprenylated%20..........pdf text en http://repository.unair.ac.id/63045/3/Bukti%20C15%20Peer%20reviewer%20dan%20validasi%20Kadep.pdf Tanjung, Mulyadi and Saputri, Ratih Dewi and Fitriati, Faiz Fakhriah and Tjahjandarie, Tjitjik Srie (2016) Antimalarial and Antioxidant Activities of Isoprenylated Coumarins from the Stem Bark of Mesua borneensis L. Journal of Biologically Active Products from Nature, 6 (2). pp. 95-100. ISSN 2231-1874 http://dx.doi.org/10.1080/22311866.2016.1188726
institution	Universitas Airlangga
building	Universitas Airlangga Library
country	Indonesia
collection	UNAIR Repository
language	English English English
topic	QD Chemistry
spellingShingle	QD Chemistry Tanjung, Mulyadi Saputri, Ratih Dewi Fitriati, Faiz Fakhriah Tjahjandarie, Tjitjik Srie Antimalarial and Antioxidant Activities of Isoprenylated Coumarins from the Stem Bark of Mesua borneensis L.
description	The aim of this study was to assess the antimalarial and antioxidant effects of the n-hexane and ethyl acetate extracts together with three isolated isoprenylated coumarins, mammea A/BA(1),mammea A/ AA cyclo D (2) and mesuol (3) from the stem bark of M. borneensis L. The n-hexane and ethyl acetate extracts, as well as compounds 1-3 were evaluated for their antimalarial activity against Plasmodium falciparum strain 3D7 (chloroquine-sensitive) and their antioxidant activity against DPPH radical scavenging. Compound 2 exhibited slightly more active than chloroquine. Compounds 1 and 3 showed very high activity against DPPH radical.
format	Article PeerReviewed
author	Tanjung, Mulyadi Saputri, Ratih Dewi Fitriati, Faiz Fakhriah Tjahjandarie, Tjitjik Srie
author_facet	Tanjung, Mulyadi Saputri, Ratih Dewi Fitriati, Faiz Fakhriah Tjahjandarie, Tjitjik Srie
author_sort	Tanjung, Mulyadi
title	Antimalarial and Antioxidant Activities of Isoprenylated Coumarins from the Stem Bark of Mesua borneensis L.
title_short	Antimalarial and Antioxidant Activities of Isoprenylated Coumarins from the Stem Bark of Mesua borneensis L.
title_full	Antimalarial and Antioxidant Activities of Isoprenylated Coumarins from the Stem Bark of Mesua borneensis L.
title_fullStr	Antimalarial and Antioxidant Activities of Isoprenylated Coumarins from the Stem Bark of Mesua borneensis L.
title_full_unstemmed	Antimalarial and Antioxidant Activities of Isoprenylated Coumarins from the Stem Bark of Mesua borneensis L.
title_sort	antimalarial and antioxidant activities of isoprenylated coumarins from the stem bark of mesua borneensis l.
publisher	Har Krishan Bhalla & Sons
publishDate	2016
url	http://repository.unair.ac.id/63045/1/Cover.pdf http://repository.unair.ac.id/63045/2/Bukti%20C15.%20Antimalarial%20and%20Antioxidant%20Activities%20of%20Isoprenylated%20..........pdf http://repository.unair.ac.id/63045/3/Bukti%20C15%20Peer%20reviewer%20dan%20validasi%20Kadep.pdf http://repository.unair.ac.id/63045/ http://dx.doi.org/10.1080/22311866.2016.1188726
_version_	1681148551805009920

Antimalarial and Antioxidant Activities of Isoprenylated Coumarins from the Stem Bark of Mesua borneensis L.

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