Effect of sodium alginate concentration on characteristic, viability, and antibacterial activity of probiotic-alginate microparticles

Probiotic (Lactobacillus acidophilus) has been known as an effective antibacterial activity, however storage, high oxygen levels, and gastric acid condition was generally decrease the probiotic viability. To maintain the probiotics’ viability, extrusion technique was selected to produce microparti...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Dewi, Melani Hariyadi, Tutiek, Purwanti
التنسيق: مقال PeerReviewed
اللغة:English
Indonesian
منشور في: Atom and Cell Publisher 2015
الموضوعات:
الوصول للمادة أونلاين:http://repository.unair.ac.id/56085/2/wKyW04.pdf
http://repository.unair.ac.id/56085/1/4.%20Peer%20Review%20Effect%20of%20sodium%20alginate%20concentration%20on%20characteristic%2Cviability%2Cand%20Antibacterial%20activity%20of%20probiotic-alginate%20microparticles.pdf
http://repository.unair.ac.id/56085/
http://www.wjpsonline.org/issue.php?id=MjY=
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الوصف
الملخص:Probiotic (Lactobacillus acidophilus) has been known as an effective antibacterial activity, however storage, high oxygen levels, and gastric acid condition was generally decrease the probiotic viability. To maintain the probiotics’ viability, extrusion technique was selected to produce microparticles. This technique used sodium alginate polymer and calcium chloride cross linking solution. This research investigated effect of sodium alginate concentration on the physical characteristics, viability and antibacterial activity. Results showed that increasing alginate concentration from 2.5% to 3.5% increased microparticle size (from 15.40µm to 37.53µm). Viability of Lactobacillus acidophillus of all formulas were above 94%, however an increased of alginate concentration did not significantly affect antibacterial activity. The extrusion method demonstrated its potential in encapsulation of Lactobacillus acidophillus for probiotics delivery.