Faktor Yang Mempengaruhi Variasi Titer Anti Hbsag Pada Post Pemberian Vaksin Hepatitis B Pada Pasien Ckd On Hd Di Rumah Sakit Premier Surabaya
Hemodialisis patients are very susceptible to infection, which can decrease in immune response. Variations titers Anti HBSAg thatoccur in patientswhoroutinelyrun Hemodialysisfollowing administration ofhepatitis B vaccinecouldbean increase, decreaseor negativeantibodies. Variationsrespon immune o...
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الملخص: | Hemodialisis patients are very susceptible to infection, which can
decrease in immune response. Variations titers Anti HBSAg thatoccur in
patientswhoroutinelyrun Hemodialysisfollowing administration ofhepatitis B
vaccinecouldbean increase, decreaseor negativeantibodies. Variationsrespon immune
of antibodiesin patients withCKDwho receivedHepatitisBvaccineat this timeis
influencedbyseveralfactors such as:increased levels ofurea, albumin, increased levels
offerritin, andadequacy ofHD.The aims of this studywas to determinethe factorsthat
influencevariationsof Anti-HBsAg titers whichincreasein CKD
patientswhoundergoroutineHemodialysisinPremier Hospital.
Thisresearchusesdescriptive method, by correlation analyzingdatabetweenelevated
levels ofurea, albumin, increased levels offerritin, andadequacy ofHD.
Descriptivecorrelation designwas used in this study with
crosssectionalapproach analytical,the number of hemodialysis patientsinPremier
Hospitalas many as36people. The population inthis studywere23 patients
undergoingregularHemodialysisinPremier SurabayaHospital whomet to the inclusion
criteria.Resultusing purposive sampling technique. Researchers conducted
alaboratoryanalysis of the resultsofurea,Anti HBSAg, ferritin, albuminin
MaytoAugust,andanalyzedthe factorsthat influencevariation ofAnti HBSAg. Result
of this study showed significant corelation beatween levels of urea in HD patients
was very influential in the variation of Anti HBSAg post Hepatitis B vaccine with
p=0,28, significan level<5%, there were corelation beatween variation of Anti
HBSAg and feritin level with p=0,040 , significan level<5%, there were corelation
beatween variation of Anti HBSAg and Albumin level with p=0,326 , significan
level<5%, there were corelation beatween variation of Anti HBSAg and adekuasi
HD level with p=0,285, significan level<5%,
The conclution of this research was that the significant corelation exists
between increased levels ofurea, albumin, increased levels offerritin, andadequacy
ofHD on variationsof antibodiesin patients withCKDwho receivedHepatitisBvaccine
pasient. |
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