การศึกษาผลของอุณหภูมิที่มีต่อการเคลื่อนที่ของอนุภาคระดับนาโนบนเยื่อไขมันสองชั้น

• Main Author: ภัทรวรรณ ไชยเสวี
• Other Authors: ศุภศร วนิชเวชารุ่งเรือง
• Format: Senior Project
• Language: Thai
• Published: จุฬาลงกรณ์มหาวิทยาลัย 2015
• Subjects: เยื่อหุ้มเซลล์; อนุภาคนาโน; Cell membrane; Nanoparticles
• Online Access: https://digiverse.chula.ac.th/Info/item/dc:9930
• Institution: Chulalongkorn University

Cell membranes are crucial to the cells. They enclose and separate the cell from extracellular environment. Structural organization of cell membranes is significant for normal cellular function. Any changes in its molecular composition can induce membrane restructuring. In this work, we have studied the effect of temperature on the movement of nanoparticles on lipid bilayer membranes. We mimicked cell system using liposomes that were produce by hydration method. Polystyrene nanoparticles were used as representative nanoparticles. Adhesion of particles on liposome was facilitated by calcium ion solution. The results indicated that increasing temperature can cause aggregation of nanoparticles on the lipid bilayer membrane. We anticipate this work to open new possibilities for the understanding of membrane structure and their functions.