อันตรกิริยาของผลไม้กับยารักษามะเร็ง
Fruits are one kind of food which has been widely consumed. However, some fruits have reported altering the Cytochrome P450 enzyme and P-glycoprotein (P-gp). Fruit-drug interaction can occur when taken together. The list of fruits that have been reported to change the action of the enzymes and P-gp...
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| Main Authors: | , |
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| 格式: | Article |
| 語言: | Thai |
| 出版: |
คณะเภสัชศาสตร์ มหาวิทยาลัยขอนแก่น
2022
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| 主題: | |
| 在線閱讀: | https://digiverse.chula.ac.th/Info/item/dc:7186 https://he01.tci-thaijo.org/index.php/IJPS/article/view/255580 |
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| 機構: | Chulalongkorn University |
| 語言: | Thai |
| 總結: | Fruits are one kind of food which has been widely consumed. However, some fruits have reported altering the Cytochrome P450 enzyme and P-glycoprotein (P-gp). Fruit-drug interaction can occur when taken together. The list of fruits that have been reported to change the action of the enzymes and P-gp includes Grapefruit, Star fruit, Pineapple, and Pomelo. Thus, it might change cancer drug levels, affecting efficacy and adverse effect of treatment. Most data of fruit-drug interaction come from in vivo studies. Data of human clinical study is limited. However, the available data can be applied to monitoring adverse drug reactions of anti-cancer medications, pharmaceutical care in cancer patients, and providing information about consuming fruits safely in patients undergoing systemic medicines for cancers. |
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