A phase 2 trial of HQK-1001 in HbE-β thalassemia demonstrates HbF induction and reduced anemia

بواسطة Poramin Patthamalai, Suthat Fuchareon, Nattawara Chaneiam, Richard G. Ghalie, David H.K. Chui, Michael S. Boosalis, Susan P. Perrine
منشور في 2018

Therapeutic fetal-globin inducers reduce transcriptional repression in hemoglobinopathy erythroid progenitors through distinct mechanisms

بواسطة Yan Dai, Jose Sangerman, Hong Yuan Luo, Suthat Fucharoen, David H.K. Chui, Douglas V. Faller, Susan P. Perrine
منشور في 2018

Fetal globin gene inducers: Novel agents and new potential

بواسطة Susan P. Perrine, Serguei A. Castaneda, David H.K. Chui, Douglas V. Faller, Ronald J. Berenson, Noppadol Siritanaratku, Suthat Fucharoen
منشور في 2018

A randomized phase I/II trial of HQK-1001, an oral fetal globin gene inducer, in β-thalassaemia intermedia and HbE/β-thalassaemia

بواسطة Suthat Fucharoen, Adlette Inati, Noppadol Siritanaratku, Swee L. Thein, William C. Wargin, Suzanne Koussa, Ali Taher, Nattawara Chaneim, Michael Boosalis, Ronald Berenson, Susan P. Perrine
منشور في 2018