Virus infection drives IL-2 antibody complexes into pro-inflammatory agonists in mice

by Lee, W.W.L, Teo, T.-H, Lum, F.-M, Andiappan, A.K, Amrun, S.N, Rénia, L, Rötzschke, O, Ng, L.F.P
Published 2020

Antibody-mediated enhancement aggravates chikungunya virus infection and disease severity

by Lum, F.-M, Couderc, T, Chia, B.-S, Ong, R.-Y, Her, Z, Chow, A, Leo, Y.-S, Kam, Y.-W, Rénia, L, Lecuit, M, Ng, L.F.P
Published 2020

Co-infection with Chikungunya virus alters trafficking of pathogenic CD8+ T cells into the brain and prevents Plasmodium-induced neuropathology

by Teo, T.-H, Howland, S.W, Claser, C, Gun, S.Y, Poh, C.M, Lee, W.W.L, Lum, F.-M, Ng, L.F.P, Rénia, L
Published 2020

Type i interferon shapes the quantity and quality of the anti-zika virus antibody response

by Yi-Pin Lee, C., Carissimo, G., Chen, Z., Lum, F.-M., Abu Bakar, F., Rajarethinam, R., Teo, T.-H., Torres-Ruesta, A., Renia, L., Ng, L.F.P.
Published 2021

Paradoxical effect of chloroquine treatment in enhancing chikungunya virus infection

by Roques, P, Thiberville, S.-D, Dupuis-Maguiraga, L, Lum, F.-M, Labadie, K, Martinon, F, Gras, G, Lebon, P, Ng, L.F.P, de Lamballerie, X, Le Grand, R
Published 2020

Viperin controls chikungunya virus-specific pathogenic T cell IFN? Th1 stimulation in mice

by Carissimo, G., Teo, T.-H., Chan, Y.-H., Lee, C.Y.-P., Lee, B., Torres-Ruesta, A., Tan, J.J.L., Chua, T.-K., Fong, S.-W., Lum, F.-M., Ng, L.F.P.
Published 2021

Plasmodium co-infection protects against chikungunya virus-induced pathologies

by Teo, T.-H, Lum, F.-M, Ghaffar, K, Chan, Y.-H, Amrun, S.N, Tan, J.J.L, Lee, C.Y.P, Chua, T.-K, Carissimo, G, Lee, W.W.L, Claser, C, Rajarethinam, R, Rénia, L, Ng, L.F.P
Published 2020

Novel differential linear B-cell epitopes to identify Zika and dengue virus infections in patients

by Amrun, S.N., Yee, W.-X., Abu Bakar, F., Lee, B., Kam, Y.-W., Lum, F.-M., Tan, J.J.L., Lim, V.W.X., Watthanaworawit, W., Ling, C., Nosten, F., Renia, L., Leo, Y.-S., Ng, L.F.P.
Published 2021

Longitudinal [18F]FB-IL-2 PET Imaging to Assess the Immunopathogenicity of O'nyong-nyong Virus Infection

by Chan, Y.-H., Teo, T.-H., Torres-Ruesta, A, Hartimath, S.V., Chee, R.S.-L., Khanapur, S., Yong, F.F., Ramasamy, B., Cheng, P., Rajarethinam, R., Robins, E.G., Goggi, J.L., Lum, F.-M., Carissimo, G., Rénia, L., Ng, L.F.P.
Published 2021

Mutating chikungunya virus non-structural protein produces potent live-attenuated vaccine candidate

by Chan, Y.-H., Teo, T.-H., Utt, A., Tan, J.J.L., Amrun, S.N., Abu Bakar, F., Yee, W.-X., Becht, E., Lee, C.Y.-P., Lee, B., Rajarethinam, R., Newell, E., Merits, A., Carissimo, G., Lum, F.-M., Ng, L.F.P.
Published 2021

Zika virus infection preferentially counterbalances human peripheral monocyte and/or NK cell activity

by Lum, F.-M, Lee, D, Chua, T.-K, Tan, J.J, Lee, C.Y.P, Liu, X, Fang, Y, Lee, B, Yee, W.-X, Rickett, N.Y, Chia, P.-Y, Lim, V, Leo, Y.-S, Matthews, D.A, Hiscox, J.A, Nga, L.F.P
Published 2020

Cross-reactive dengue human monoclonal antibody prevents severe pathologies and death from Zika virus infections

by Kam, Y.-W, Lee, C.Y.-P, Teo, T.-H, Howland, S.W, Amrun, S.N, Lum, F.-M, See, P, Kng, N.Q.-R, Huber, R.G, Xu, M.-H, Tan, H.-L, Choo, A, Maurer-Stroh, S, Ginhoux, F, Fink, K, Wang, C.-I, Ng, L.F, R‚nia, L
Published 2020

Multimodal assessments of Zika virus immune pathophysiological responses in marmosets

by Lum, F.-M, Zhang, W, Lim, K.-C, Malleret, B, Teo, T.-H, Koh, J.-J, Lee, K.J, Chua, T.-K, Kam, Y.-W, Yee, W.-X, Huen, I, Tan, J.J.L, Amrun, S.N, Prakash KN, B, Cozzone, P.J, Renia, L, Lee, P.T.H, Ng, L.F.P
Published 2020

Loss of TLR3 aggravates CHIKV replication and pathology due to an altered virus-specific neutralizing antibody response

by Her, Z, Teng, T.-S, Tan, J.J.L, Teo, T.-H, Kam, Y.-W, Lum, F.-M, Lee, W.W.L, Gabriel, C, Melchiotti, R, Andiappan, A.K, Lulla, V, Lulla, A, Win, M.K, Chow, A, Biswas, S.K, Leo, Y.-S, Lecuit, M, Merits, A, Rénia, L, Ng, L.F.P
Published 2020

Immunological observations and transcriptomic analysis of trimester-specific full-term placentas from three Zika virus-infected women

by Lum, F.-M., Narang, V., Hue, S., Chen, J., McGovern, N., Rajarethinam, R., Tan, J.J.L., Amrun, S.N., Chan, Y.-H., Lee, C.Y.P., Chua, T.-K., Yee, W.-X., Yeo, N.K.W., Tan, T.-C., Liu, X., Haldenby, S., Leo, Y.-S., Ginhoux, F., Chan, J.K.Y., Hiscox, J., Chong, C.-Y., Ng, L.F.P.
Published 2021