P53: Updates on mechanisms, biology and therapy (I)

بواسطة Lane, D.P., Verma, C.S.
منشور في 2021

Understanding p53 functions through p53 antibodies

بواسطة Sabapathy, K., Lane, D.P.
منشور في 2021

Long range recognition and selection in IDPs: The interactions of the C-terminus of p53

بواسطة Kannan, S, Lane, D.P, Verma, C.S
منشور في 2020

Mapping the structural and dynamical features of multiple p53 DNA binding domains: Insights into loop 1 intrinsic dynamics

بواسطة Lukman, S., Lane, D.P., Verma, C.S.
منشور في 2014

Systematic mutational analysis of an ubiquitin ligase (MDM2)-binding peptide: Computational studies

بواسطة Liu, Y., Lane, D.P., Verma, C.S.
منشور في 2014

Stapled BH3 Peptides against MCL-1: Mechanism and Design Using Atomistic Simulations

بواسطة Joseph, T.L., Lane, D.P., Verma, C.S.
منشور في 2014

Why is F19Ap53 unable to bind MDM2? Simulations suggest crack propagation modulates binding

بواسطة Dastidar, S.G., Lane, D.P., Verma, C.S.
منشور في 2014

Modulation of p53 binding to MDM2: Computational studies reveal important roles of Tyr100

بواسطة Dastidar, S.G., Lane, D.P., Verma, C.S.
منشور في 2014

Characterizing the conformational landscape of MDM2-binding p53 peptides using Molecular Dynamics simulations

بواسطة Yadahalli, S, Li, J, Lane, D.P, Gosavi, S, Verma, C.S
منشور في 2020

The dual interactions of p53 with MDM2 and p300: Implications for the design of MDM2 inhibitors

بواسطة Kannan, S., Partridge, A.W., Lane, D.P., Verma, C.S.
منشور في 2021

Mechanism of stapled peptide binding to MDM2: Possible consequences for peptide design

بواسطة Sim, A.Y.L., Joseph, T., Lane, D.P., Verma, C.
منشور في 2014

Anti-c-Met antibodies recognising a temperature sensitive epitope, inhibit cell growth

بواسطة Wong, J.S, Warbrick, E, Vojtesk, B, Hill, J, Lane, D.P
منشور في 2020

A comparison and optimization of methods and factors affecting the transformation of Escherichia coli

بواسطة Chan, W.-T., Verma, C.S., Lane, D.P., Gan, S.K.-E.
منشور في 2014

On the origin of the stereoselective affinity of Nutlin-3 geometrical isomers for the MDM2 protein

بواسطة ElSawy, K.M., Verma, C.S., Lane, D.P., Caves, L.S.D.
منشور في 2014

High Mdm4 levels suppress p53 activity and enhance its half-life in acute myeloid leukaemia

بواسطة Tan, B.X, Khoo, K.H, Lim, T.M, Lane, D.P
منشور في 2020

Differences in the transactivation domains of p53 family members: A computational study

بواسطة Mavinahalli, J.N, Madhumalar, A, Beuerman, R.W, Lane, D.P, Verma, C
منشور في 2020

Improved eIF4E Binding Peptides by Phage Display Guided Design: Plasticity of Interacting Surfaces Yield Collective Effects

بواسطة Zhou, W., Quah, S.T., Verma, C.S., Liu, Y., Lane, D.P., Brown, C.J.
منشور في 2014

The hot-spot p53R172H mutant promotes formation of giant spermatogonia triggered by DNA damage

بواسطة Xue, Y, Raharja, A, Sim, W, Wong, E.S.M, Rahmat, S.A.B, Lane, D.P
منشور في 2020

Conservation of all three p53 family members and Mdm2 and Mdm4 in the cartilaginous fish

بواسطة Lane, D.P., Madhumalar, A., Lee, A.P., Tay, B.-H., Verma, C., Brenner, S., Venkatesh, B.
منشور في 2014

Inhibition of NLRP3 inflammasome activation by cell-permeable stapled peptides

بواسطة Pal, A., Neo, K., Rajamani, L., Ferrer, F.J., Lane, D.P., Verma, C.S., Mortellaro, A.
منشور في 2021