Mutations in LRRK2 increase phosphorylation of peroxiredoxin 3 exacerbating oxidative stress-induced neuronal death

由 Angeles, D.C., Gan, B.-H., Onstead, L., Zhao, Y., Lim, K.-L., Dachsel, J., Melrose, H., Farrer, M., Wszolek, Z.K., Dickson, D.W., Tan, E.-K.
出版 2014

The G2019S LRRK2 mutation is uncommon in an Asian cohort of Parkinson's disease patients

由 Tan E.K., Shen H., Tan L.C.S., Farrer M., Yew K., Chua E., Jamora R.D., Puvan K., Puong K.Y., Zhao Y., Pavanni R., Wong M.C., Yih Y., Skipper L., Liu J.-J.
出版 2018

Analysis of LRRK2 functional domains in nondominant Parkinson disease

由 Skipper L., Shen H., Chua E., Bonnard C., Kolatkar P., Tan L.C.S., Jamora R.D., Puvan K., Puong K.Y., Zhao Y., Pavanni R., Wong M.C., Yuen Y., Farrer M., Liu J.J., Tan E.K.
出版 2018

Analysis of Lrrk2 R1628P as a risk factor for Parkinson's disease

由 Ross, O.A., Wu, Y.-R., Lee, M.-C., Funayama, M., Chen, M.-L., Soto, A.I., Mata, I.F., Lee-Chen, G.-J., Chiung, M.C., Tang, M., Zhao, Y., Hattori, N., Farrer, M.J., Tan, E.-K., Wu, R.-M.
出版 2014

Collaborative analysis of alpha-synuclein gene promoter variability and Parkinson disease

由 Maraganore D.M., De Andrade M., Elbaz A., Farrer M.J., Ioannidis J.P., Kruger R., Rocca W.A., Schneider N.K., Lesnick T.G., Lincoln S.J., Hulihan M.M., Aasly J.O., Ashizawa T., Chartier-Harlin M.-C., Checkoway H., Ferrarese C., Hadjigeorgiou G., Hattori N., Kawakami H., Lambert J.-C., Lynch T., Mellick G.D., Papapetropoulos S., Parsian A., Quattrone A., Riess O., Tan E.-K., Van Broeckhoven C.
出版 2018

Lrrk2 R1441C parkinsonism is clinically similar to sporadic Parkinson disease

由 Haugarvoll K., Rademakers R., Kachergus J.M., Nuytemans K., Ross O.A., Gibson J.M., Tan E.-K., Gaig C., Tolosa E., Goldwurm S., Guidi M., Riboldazzi G., Brown L., Walter U., Benecke R., Berg D., Gasser T., Theuns J., Pals P., Cras P., De Deyn P.P., Engelborghs S., Pickut B., Uitti R.J., Foroud T., Nichols W.C., Hagenah J., Klein C., Samii A., Zabetian C.P., Bonifati V., Van Broeckhoven C., Farrer M.J., Wszolek Z.K.
出版 2018

Evaluation of the interaction between LRRK2 and PARK16 loci in determining risk of Parkinson's disease: analysis of a large multicenter study

由 Wang L., Heckman M.G., Aasly J.O., Annesi G., Bozi M., Chung S.J., Clarke C., Crosiers D., Eckstein G., Garraux G., Hadjigeorgiou G.M., Hattori N., Jeon B., Kim Y.J., Kubo M., Lesage S., Lin J.J., Lynch T., Lichtner P., Mellick G.D., Mok V., Morrison K.E., Quattrone A., Satake W., Silburn P.A., Stefanis L., Stockton J.D., Tan E.K., Toda T., Brice A., Van Broeckhoven C., Uitti R.J., Wirdefeldt K., Wszolek Z., Xiromerisiou G., Maraganore D.M., Gasser T., Krüger R., Farrer M.J., Ross O.A., Sharma M.
出版 2018

A large-scale genetic association study to evaluate the contribution of Omi/HtrA2 (PARK13) to Parkinson's disease

由 Krüger R., Sharma M., Riess O., Gasser T., Van Broeckhoven C., Theuns J., Aasly J., Annesi G., Bentivoglio A.R., Brice A., Djarmati A., Elbaz A., Farrer M., Ferrarese C., Gibson J.M., Hadjigeorgiou G.M., Hattori N., Ioannidis J.P.A., Jasinska-Myga B., Klein C., Lambert J.-C., Lesage S., Lin J.-J., Lynch T., Mellick G.D., de Nigris F., Opala G., Prigione A., Quattrone A., Ross O.A., Satake W., Silburn P.A., Tan E.K., Toda T., Tomiyama H., Wirdefeldt K., Wszolek Z., Xiromerisiou G., Maraganore D.M.
出版 2018

Large-scale assessment of polyglutamine repeat expansions in Parkinson disease

由 Wang L., Aasly J.O., Annesi G., Bardien S., Bozi M., Brice A., Carr J., Chung S.J., Clarke C., Crosiers D., Deutschländer A., Eckstein G., Farrer M.J., Goldwurm S., Garraux G., Hadjigeorgiou G.M., Hicks A.A., Hattori N., Klein C., Jeon B., Kim Y.J., Lesage S., Lin J.-J., Lynch T., Lichtner P., Lang A.E., Mok V., Jasinska-Myga B., Mellick G.D., Morrison K.E., Opala G., PihlstrØm L., Pramstaller P.P., Park S.S., Quattrone A., Rogaeva E., Ross O.A., Stefanis L., Stockton J.D., Silburn P.A., Theuns J., Tan E.K., Tomiyama H., Toft M., Van Broeckhoven C., Uitti R.J., Wirdefeldt K., Wszolek Z., Xiromerisiou G., Yueh K.-C., Zhao Y., Gasser T., Maraganore D.M., Krüger R., Sharma M.
出版 2018

Large-scale replication and heterogeneity in Parkinson disease genetic loci

由 Sharma M., Ioannidis J.P.A., Aasly J.O., Annesi G., Brice A., Van Broeckhoven C., Bertram L., Bozi M., Crosiers D., Clarke C., Facheris M., Farrer M., Garraux G., Gispert S., Auburger G., Vilariño-Güell C., Hadjigeorgiou G.M., Hicks A.A., Hattori N., Jeon B., Lesage S., Lill C.M., Lin J.-J., Lynch T., Lichtner P., Lang A.E., Mok V., Jasinska-Myga B., Mellick G.D., Morrison K.E., Opala G., Pramstaller P.P., Pichler I., Park S.S., Quattrone A., Rogaeva E., Ross O.A., Stefanis L., Stockton J.D., Satake W., Silburn P.A., Theuns J., Tan E.-K., Toda T., Tomiyama H., Uitti R.J., Wirdefeldt K., Wszolek Z., Xiromerisiou G., Yueh K.-C., Zhao Y., Gasser T., Maraganore D., Krüger R.
出版 2018

Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease

由 Sidransky, E., Nalls, M.A., Aasly, J.O., Aharon-Peretz, J., Annesi, G., Barbosa, E.R., Bar-Shira, A., Berg, D., Bras, J., Brice, A., Chen, C.-M., Clark, L.N., Condroyer, C., De Marco, E.V., Dürr, A., Eblan, M.J., Fahn, S., Farrer, M.J., Fung, H.-C., Gan-Or, Z., Gasser, T., Gershoni-Baruch, R., Giladi, N., Griffith, A., Gurevich, T., Januario, C., Kropp, P., Lang, A.E., Lee-Chen, G.-J., Lesage, S., Marder, K., Mata, I.F., Mirelman, A., Mitsui, J., Mizuta, I., Nicoletti, G., Oliveira, C., Ottman, R., Orr-Urtreger, A., Pereira, L.V., Quattrone, A., Rogaeva, E., Rolfs, A., Rosenbaum, H., Rozenberg, R., Samii, A., Samaddar, T., Schulte, C., Sharma, M., Singleton, A., Spitz, M., Tan, E.-K., Tayebi, N., Toda, T., Troiano, A.R., Tsuji, S., Wittstock, M., Wolfsberg, T.G., Wu, Y.-R., Zabetian, C.P., Zhao, Y., Ziegler, S.G.
出版 2014

A multi-centre clinico-genetic analysis of the VPS35 gene in Parkinson disease indicates reduced penetrance for disease-associated variants

由 Sharma M., Ioannidis J.P.A., Aasly J.O., Annesi G., Brice A., Bertram L., Bozi M., Barcikowska M., Crosiers D., Clarke C.E., Facheris M.F., Farrer M., Garraux G., Gispert S., Auburger G., Vilariño-Güell C., Hadjigeorgiou G.M., Hicks A.A., Hattori N., Jeon B.S., Jamrozik Z., Krygowska-Wajs A., Lesage S., Lill C.M., Lin J.-J., Lynch T., Lichtner P., Lang A.E., Libioulle C., Murata M., Mok V., Jasinska-Myga B., Mellick G.D., Morrison K.E., Meitnger T., Zimprich A., Opala G., Pramstaller P.P., Pichler I., Park S.S., Quattrone A., Rogaeva E., Ross O.A., Stefanis L., Stockton J.D., Satake W., Silburn P.A., Strom T.M., Theuns J., Tan E.K., Toda T., Tomiyama H., Uitti R.J., Van Broeckhoven C., Wirdefeldt K., Wszolek Z., Xiromerisiou G., Yomono H.S., Yueh K.-C., Zhao Y., Gasser T., Maraganore D., Krüger R.
出版 2018